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    10:15 - 11:00 | Balancing Act: DNA Sensing Pathways in Health and Disease
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    Katherine A. Fitzgerald - University of Massachusetts Chan Medical School, United States
    11:00 - 11:30 | Why so many ways to die?
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    Vishva M. Dixit - Genentech, Inc., United States
    11:30 - 11:45 | TLR4-Driven Macrophage Priming Regulates Thymic Size Through Enhanced Efferocytosis
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    Andri Lemarquis - City of Hope (COH), United States
    11:45 - 12:00 | TLR7-9 ADAPTORS TASL AND TASL2 MEDIATE IRF5-DEPENDENT ANTIVIRAL RESPONSES AND AUTOIMMUNITY.
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    Manuele Rebsamen - Dpt. of Immunobiology, University of Lausanne, Switzerland
    12:00 - 12:15 | SINGLE STRANDED DNA SENSING IS ASSOCIATED WITH ACTIVATION OF INFLAMMATORY AND DNA DAMAGE RESPONSES INDEPENDENTLY OF CANONICAL NUCLEIC ACID DETECTION PATHWAYS
     
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    Roger-Junior Eloiflin - IGMM, Université de Montpellier, CNRS, France
    12:00 - 12:15 | NEUTROPHILS ARE THE EARLIEST INNATE SENSORS OF PRENEOPLASTIC MAMMARY EPITHELIAL CELLS
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    Antoine Debiesse - Centre de Recherche en Cancérologie de Lyon (CRCL), France
    12:00 - 12:15 | SURVIVAL MECHANISMS OF TUMOR-ASSOCIATED NEUTROPHILS IN A MOUSE MODEL OF LUNG SQUAMOUS CELL CARCINOMA
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    Abdullah Mayet - Department of Molecular Biology, Université Libre de Bruxelles, Belgium
    12:00 - 12:15 | APOPTOTIC CASPASES SILENCE SPONTANEOUS INNATE IMMUNE SIGNALS BY SPECIFICALLY CLEAVING ACTIVATED MITOCHONDRIAL ANTIVIRAL SIGNALING PROTEIN (MAVS)
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    Pallab Chakraborty - Faculty of Biology, University of Freiburg, Germany
    12:00 - 12:15 | Crosslinking of Ly6a metabolically reprogram CD8 T cells for cancer immunotherapy.
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    Avishai Maliah - Tel Aviv University , Israel
    12:00 - 12:15 | LIPID METABOLISM PROFILING OF DIFFUSE LARGE B-CELL LYMPHOMA CELLS PREDICTS SENSITIVITY TO FERROPTOSIS
     
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    Véronique Baud - Inserm, Université Paris Cité, NF-κB, Differentiation and Cancer, France
    12:00 - 12:15 | Validation of new mTOR regulatory genes identified in a human NK cell CRISPR/Cas9 screen
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    Emily Sible - CIRI, Centre International de Recherche en Infectiologie, Univ. Lyon, Inserm, U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, ENS de Lyon, France
    14:00 - 14:30 | Microbial viability drives immunometabolic responses of macrophages
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    Johan Garaude - Mitochondrial Biology and Innate Immunity ImmunoConcEpT, University of Bordeaux, France
    14:30 - 15:00 | Agents of Progression and Protection: How Innate Immunity Shapes Metastasis
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    Mikala Egeblad - John Hopkins University, United States
    15:00 - 15:30 | Functional analysis of natural variants in diagnosis of autoinflammatory diseases, and understanding of inflammasome regulation
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    Bénédicte Py - Centre International de Recherche en Infectiologie , France
    15:30 - 15:45 | From Injection Site to Insight: Translating clinical signals in NextGen mRNA Vaccines
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    Brian Schanen - Sanofi, United States
    16:15 - 16:45 | Metabolic reprogramming of cancer immunity: a functional genomics perspective
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    Hongbo Chi - St. Jude Children’s Research Hospital , United States
    16:45 - 17:00 | TIGAR: A KEY METABOLIC MODULATOR GOVERNING CD4 T CELL METABOLISM AND FATE
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    Elpida Bokou Gianneli - Université de Montréal, 2900, Bd Édouard-Montpetit, Montréal (Qc) H3T 1J4, Centre de Recherche Hôpital Maisonneuve Rosemont, 5415, Bd de l'Assomption Montréal (Qc) H1T 2M4, Canada
    17:00 - 17:30 | Use of carbon sources in human and murine natural killer cells: variation on a common theme.
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    Antoine Marçais - Centre International de Recherche en Infectiologie , France
    17:30 - 17:45 | EXPLORING TCR-DEPENDENT METABOLIC IMPRINTING OF ANTI-VIRAL T CELL RESPONSES
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    Hannah Bollons - University of Birmingham, United Kingdom
    17:45 - 18:15 | Increasing CAR T cell persistence instructed by basic immuno-metabolic principles
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    Christopher Hess - University of Basel, Switzerland
    09:00 - 09:30 | Diagnosis of infectious and inflammatory diseases by RNA molecular signatures:  Towards a  Molecular Taxonomy of infectious and inflammatory diseases.
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    Michael Levin - Imperial College London, United Kingdom
    09:30 - 09:45 | DPP9-mediated Inflammasome Repression Protects Against Checkpoint Inhibitor Pneumonitis
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    Ricky Brewer - Yale University, United States
    09:45 - 10:15 | Overcoming Resistance to PD-1 Checkpoint Blockade for Cancer Immunotherapy
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    Arlene H. Sharpe - Harvard Medical School, United States
    10:15 - 10:30 | Effector T lymphocytes can initiate spontaneous cancers
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    valentin Thevin - CRCL, France
    11:00 - 11:30 | Decoding the mode of action of tumor immunotherapies in vivo
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    Philippe Bousso - Institut Pasteur , France
    11:30 - 11:45 | Age is a critical driver of the pediatric tumour microenvironment and the response to immunotherapy
     
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    Willem Joost Lesterhuis - The Kids Research Institute Australia, Australia
    11:45 - 12:00 | Tumor specific regulation of T cell exhaustion can be targeted for immunotherapy
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    Gregory Verdeil - Department of Oncology, UNIL CHUV, University of Lausanne, Switzerland
    12:00 - 12:30 | Regulation of T-cell responses to cancer by the NF-kappaB family of transcription factors.
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    Yenkel Grinberg-Bleyer - Cancer Research Center of Lyon, France
    12:30 - 12:45 | ROLE OF INFLAMMATION AND TRANSCRIPTION FACTOR FOXO1 ON T-CELL EXHAUSTION IN THE COURSE OF ANTI-TUMOR IMMUNE RESPONSES
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    Amélie Lombès - Institut Cochin, INSERM U1016, CNRS 8104, Université Paris Cité, France
    12:30 - 12:45 | NON-CANONICAL TRANSLATION OF ONCOGENES IN CANCER CELLS GENERATES SHARED AND IMMUNOGENIC NEOEPITOPES
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    Anaëlle Bolon - Centre de Recherche en Cancérologie de Lyon, UMR INSERM U1052 CNRS 5286 Université Claude Bernard Lyon 1 Centre Léon Bérard, France
    12:30 - 12:45 | Disruption of RINF gene (also known as CXXC5) improves persistence and antitumoral efficacy of CAR T cell therapy
     
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    Dongjie An - Université Paris Cité, Institut Cochin, INSERM, CNRS, Equipe Labélisée Ligue Nationale Contre le Cancer , France
    12:30 - 12:45 | NF-κB2 Transcription Factor Drives CD8⁺ T-Cell Antitumor Functions
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    Khaled Bouherrou - Cancer Research Center of Lyon (CRCL) - Inserm U1052, France
    12:30 - 12:45 | IKKbeta is an intrinsic immune checkpoint in melanoma cells and predicts patients’ response to immunotherapy
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    Toby Lawrence - Centre d'Immunologie Marseille-Luminy, INSERM, France
    12:30 - 12:45 | The role of myeloid cells in skull-to-brain axis & neuroinflammation
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    Elisa Eme-Scolan - Centre d'Immunologie de Marseille Luminy, France
    12:30 - 12:45 | HTLV-1-associated cancer induces neuro-immune dysregulation correlated with disease severity
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    Fernando Yuri Nery Do Vale - Department of Clinical and Toxicological Analyses, School of Pharmaceutical Sciences, University of São Paulo (USP), Brazil
    14:30 - 15:00 | Brain borders take center stage: role of meningeal macrophages in neurocognition and neuroinflammation
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    Réjane Rua - Centre d'Immunologie de Marseille-Luminy (CIML), France
    15:00 - 15:15 | Extrafollicular generation of antibody-secreting cells in highly infiltrated ovarian tumors
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    Gabriel Chemin - Cancer Research Center of Lyon (CRCL), France
    15:15 - 15:45 | Scratching exaggerates allergic inflammation and augments host defense via neurogenic mast cell activation
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    Dan Kaplan - Departments of Dermatology and Immunology, University of Pittsburgh, United States
    16:15 - 17:00 | Neuroimmune ecosystems in health and disease
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    Henrique Veiga-Fernandes - Champalimaud Foundation, Portugal
    08:45 - 09:15 | Replication of human seasonal coronavirus HKU1 and antiviral immune responses
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    Olivier Schwartz - Virus & Immunity Unit, Institut Pasteur, France
    09:15 - 09:45 | Tumor-specific antigens (TSAs) preferentially derive from unmutated genomic sequences.
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    Claude Perreault - Université de Montréal, Canada
    09:45 - 10:00 | A cytomegalovirus-based vaccine against Lassa virus in the Mastomys natalensis rodent reservoir
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    Kyle Rosenke - National Institutes of Allergy and Infectious Disease, United States
    10:30 - 11:00 | Preclinical development of ErVac01, a viral-vectored vaccine encoding tumor epitopes derived from endogenous retrovirus sequences
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    Paola Bonaventura - ErVimmune, France - Centre de Recherche en Cancérologie de Lyon (CRCL), France
    11:00 - 11:30 | Therapeutic Vaccination in Cancer: Excitement, Challenges & Realities
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    Lélia Delamarre - Genentech, United States
    11:30 - 11:45 | DEVELOPMENT OF A NEW THERAPEUTIC VACCINATION STRATEGY BASED ON LONG ARTIFICIAL SYNTHETIC PEPTIDES IN MELANOMA.
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    Amélie Guiho - Immunology and New Concepts in ImmunoTherapy, INCIT, Nantes Université, Université d'Angers, Inserm, France
    11:30 - 11:45 | Effect of fever-range hyperthermia on the humoral immune response
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    Marie Le Borgne - INSERM U1148 “Laboratory for Vascular Translational Science”, France
    11:30 - 11:45 | Vaccination prevents immune suppression and tissue disruption in LCMV-induced Post-Acute Syndromes
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    Paula Cebollada Rica - Universitat Pompeu Fabra, Spain
    11:30 - 11:45 | HLA-E-dependent adaptations of NKG2A+ and NKG2C+ NK cells in people living with HIV
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    Emma Beaumont - Institut Pasteur, Université Paris-Cité, HIV Inflammation & Viral Persistences Unit, France
    11:30 - 11:45 | Role of the inflammasome pathway in the expansion and functions of regulatory plasma cells during sepsis
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    Clara Vigneron - Equipe Inflammasome NLRP3 et réponse immunitaire au sepsis - Centre International de Recherche en Infectiologie, France
    11:30 - 11:45 | CYLD PROTEOLYSIS BY CASPASE-3, A CHECKPOINT TO BALANCE INFLAMMATION DURING MITOCHONDRIAL APOPTOSIS?
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    Yanis Macé - SOAP Team, CRCI2NA, INSERM U1307, CNRS U6075, Nantes Université, Université d’Angers, France
    11:30 - 11:45 | Critical COVID-19 unveils the link between viral particle blood dissemination and prolonged Type I Interferon
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    William Mouton - Hospices Civils de Lyon, France
    13:15 - 13:45 | Immune responses to persistent viral infections
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    Annette Oxenius - Institute of Microbiology, ETH Zurich, Switzerland
    13:45 - 14:00 | Tlr7 expression from the inactive X chromosome in female B cells contributes to the germinal center response to virus-like particles (pathogen-like COVID-19 vaccine)
     
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    Mélissa Nieucel - Infinity Toulouse, France
    14:00 - 14:30 | Memory CD8 T Cells: Quantity, Quality, and Location
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    David Masopust - University Minnesota, United States
    14:30 - 15:00 | Regulatory Plasma Cells and rRNA Epitranscriptomic Modifications as Novel Mechanisms of Sepsis-Induced T Cell Dysfunction
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    Fabienne Venet - Centre International de Recherche en Infectiologie , France - Centre de recherche en Cancerologie de Lyon, France
    15:30 - 15:45 |  
    Non-AUG upstream open reading frame translation from viral transcripts elicits specific T cell immune responses in people living with HIV-1
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    Emiliano Ricci - LBMC - ENS de Lyon, France
    15:45 - 16:15 | Breakthrough in RSV prevention
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    Louis Bont - UMC Utrecht, Netherlands
    16:15 - 17:00 | Neuroimmune interactions regulate T cell fate and the development of type II immunity
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    Vijay K. Kuchroo - Brighten and Women’ hospital, Harvard Medical School, United States
    01 | NEUTROPHILS ARE THE EARLIEST INNATE SENSORS OF PRENEOPLASTIC MAMMARY EPITHELIAL CELLS
    topicInnate Immunity
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    Antoine Debiesse - Centre de Recherche en Cancérologie de Lyon (CRCL), France
    02 | SURVIVAL MECHANISMS OF TUMOR-ASSOCIATED NEUTROPHILS IN A MOUSE MODEL OF LUNG SQUAMOUS CELL CARCINOMA
    topicInnate Immunity
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    Abdullah Mayet - Department of Molecular Biology, Université Libre de Bruxelles, Belgium
    03 | APOPTOTIC CASPASES SILENCE SPONTANEOUS INNATE IMMUNE SIGNALS BY SPECIFICALLY CLEAVING ACTIVATED MITOCHONDRIAL ANTIVIRAL SIGNALING PROTEIN (MAVS)
    topicInnate Immunity
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    Pallab Chakraborty - Faculty of Biology, University of Freiburg, Germany
    04 | SINGLE STRANDED DNA SENSING IS ASSOCIATED WITH ACTIVATION OF INFLAMMATORY AND DNA DAMAGE RESPONSES INDEPENDENTLY OF CANONICAL NUCLEIC ACID DETECTION PATHWAYS
     
    topicInnate Immunity
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    Roger-Junior Eloiflin - IGMM, Université de Montpellier, CNRS, France
    05 | DNA damage response factor potentiates TLR3 antiviral immune responses in the endosome
    topicInnate Immunity
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    Max Bondarchenko - DNA Repair and Chemoresistance Group, Department of Cancer Research (DoCR), Luxembourg Institute of Health (LIH), Luxembourg
    06 | From scRNA-seq to Spatial transcriptomics Profiling: Custom Xenium Panel to Map Innate Immune Landscapes in Colorectal Carcinogenesis
    topicInnate Immunity
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    Pierre Duplouye - CRCL, France
    07 | THE CHAPERONE GRP94 INTERACTS WITH THE PROPROTEIN CONVERTASE FURIN AND REGULATES TGF-BETA MATURATION IN HUMAN PRIMARY M2 MACROPHAGES
    topicInnate Immunity
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    Valentin Baverel - Université Bourgogne Europe, UFR des Sciences de Santé, France
    08 | A focus on Neutrophils during the progression of human colorectal cancer to uncover their therapeutic potential
    topicInnate Immunity
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    Baptiste Martinon - CRCL, France
    09 | DISSECTING B-CELL DYSFUNCTION IN CHRONIC HEPATITIS B PATIENTS
    topicInnate Immunity
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    Amie Ceesay - Centre International de Recherche en Infectiologie, CIRI, INSERM, U1111, Lyon; , France
    10 |  
    Multiomics profiling across mammary carcinogenesis reveals an early organized immune response at preneoplastic stage
    topicInnate Immunity
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    Martial Scavino - UMR Inserm 1052 CNRS 5286, Cancer Research Center of Lyon, France
    11 | Innate immune memory induced by inactivated Rothia nasimurium confers antiviral properties in alveolar macrophages from treated pigs
    topicInnate Immunity
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    Aida Tort-Miró - IRTA, Animal Health, Centre de Recerca en Sanitat Animal (CReSA), Campus de la Universitat Autònoma de Barcelona (UAB), Spain
    12 | Harnessing DNA repair factors to promote an innate immune response against glioblastoma
     
    topicInnate Immunity
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    Ana Catarina Vales De Almeida - DNA Repair and Chemoresistance group, Department of Cancer Research, Luxembourg Institute of Health, Luxembourg
    13 | Caspase-8 suppresses neutrophil-mediated inflammation driven by tonic TNF-α signaling during homeostasis
    topicInnate Immunity
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    Germana Lentini - Department of Human Pathology “Gaetano Barresi”, University of Messina, Italy
    14 | Interleukin-35 impairs human NK cell effector functions and induces their ILC1-like conversion with tissue residency features 
    topicInnate Immunity
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    Lara Revol-Bauz - CISTAR team, Cancer Research Center of Lyon, INSERM U1052, CNRS UMR5286, Université de Lyon, Université Lyon 1, Centre Léon Bérard, F-69000 Lyon, France., France
    15 | MECHANISTIC INSIGHTS OF NK CELLS DYSFUNCTION IN A T CELL LYMPHOMA MODEL
    topicInnate Immunity
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    Anna Bossan - Centre International de Recherche en Infectiologie, France
    16 | Ribosome-Associated Proteins and Specialized Ribosomes in the Translational Control of Macrophage Inflammatory Responses
     
    topicInnate Immunity
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    Nathalie Davoust-Nataf - Laboratory of Biology and Modeling of the Cell (LBMC), CNRS UMR5239, ENS de Lyon, France
    17 | Involvement of antiviral pathways in cell death decisions and their exploitation for tumor therapy 
    topicInnate Immunity
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    Sebastian Stegmaier - Deutsches Krebsforschungszentrum, Germany
    18 | DECOUPLING IL-1β RELEASE FROM PYROPTOSIS: NOVEL INSIGHTS INTO NLRP3 INFLAMMASOME SIGNALING
     
    topicInnate Immunity
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    Lucie Collombet - CIRI, Centre International de Recherche en Infectiologie, Univ Lyon, Inserm, U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, ENS de Lyon, F-69007, France
    19 | Identification of Mediator Complex as a Key Negative Regulator of NK Cell Reactivity
    topicInnate Immunity
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    Noemi Rousseaux - CIRI, Equipe TW, France
    20 | CYTOSKELETON-RELATED PROTEINS INVOLVEMENT IN PYRIN INFLAMMASOME
    topicInnate Immunity
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    Chloé Briand - CIRI, Centre International de Recherche en Infectiologie, Universite Claude Bernard Lyon 1, Inserm U1111, CNRS, UMR5308, ENS de Lyon, France
    21 | Balanced levels between IFNγ and TGFβ1 regulate the expression by CLL cells of indoleamine 2,3-dioxygenase, a key Tryptophan catabolic enzyme in immune tumor microenvironment
    topicInnate Immunity
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    Helene Jin - INSERM UMR1349, France
    22 | Metformin reverses tumor-induced monocyte phenotype shift and restores phagocytic activity
    topicInnate Immunity
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    Mourad Aribi - Laboratory of Applied Molecular Biology and Immunology, W0414100, University of Tlemcen, Algeria
    23 | Dissemination routes of diffuse large B cell lymphoma shape differently the immune response to cancer invasion in secondary lymphoid organs.
    topicInnate Immunity
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    Kamil Chahine - Institute for Research in Biomedicine, Università della Svizzera Italiana, Switzerland
    24 | NK cells with adhesion defects and reduced cytotoxic functions are associated with a poor prognosis in Multiple Myeloma.
    topicInnate Immunity
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    Bineta Rigaud - CRCT, France
    25 | INVESTIGATING THE IMPACT OF GRANULOCYTE COLONY-STIMULATING FACTOR RECEPTOR MUTATIONS ON NEUTROPHIL FUNCTION USING ZEBRAFISH.
    topicInnate Immunity
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    Rachel Webb - School of Medicine, Deakin University, Australia
    26 | Clocking Immunity: How Circadian Rhythms Control NLRP3 Inflammasome Activity
    topicInnate Immunity
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    Léa Bardoulet - Cancer Research Center of Lyon (CRCL) - UMR INSERM 1052 - CNRS 5286 , France
    27 | Genome-wide CRISPR/Cas9 screen reveals factors that influence the susceptibility of tumor cells to NK cell-mediated killing
    topicInnate Immunity
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    Emilie Narni-Mancinelli - 1Aix Marseille Université, Centre National de la Recherche Scientifique, INSERM, Centre d'Immunologie de Marseille-Luminy, France
    28 | Validation of new mTOR regulatory genes identified in a human NK cell CRISPR/Cas9 screen
    topicImmuno-metabolism
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    Emily Sible - CIRI, Centre International de Recherche en Infectiologie, Univ. Lyon, Inserm, U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, ENS de Lyon, France
    29 | Crosslinking of Ly6a metabolically reprogram CD8 T cells for cancer immunotherapy.
    topicImmuno-metabolism
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    Avishai Maliah - Tel Aviv University , Israel
    30 | ELUCIDATING THE ROLE OF THE ACOD1-ITACONATE AXIS IN THE POLARISATION OF MICROGLIA AND MACROPHAGES UNDER INFLAMMATION
    topicImmuno-metabolism
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    Eleonora Campus - Neuro-Immunology Group, Department of Cancer Research, Luxembourg Institute of Health, Luxembourg
    31 | IMPACT OF PERSISTENT LOW-GRADE INFLAMMATION ON HIGH FAT DIET-INDUCED DIABETES IN A MOUSE MODEL
    topicImmuno-metabolism
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    Assem Duisembekova - Centre International de Recherche en Infectiologie, France
    32 | ATP citrate lyase is required to initiate acute myeloid leukemia and to rewire the leukemic metabolism and the expression of immune molecules. 
    topicImmuno-metabolism
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    Assya Khenniche - CIRI INSERM U1111, France
    33 | Study of human NK cell metabolism: the role of pyruvate and glycogen
    topicImmuno-metabolism
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    Antoine Giboudot - Centre Internationale de Recherche en Infectiologie (CIRI) Inserm U1111 - Team TW, France
    34 | NUTRIENT SENSING THROUGH THE HEXOSAMINE PATHWAY REGULATES NK CELL REACTIVITY AND ANABOLISM BUT IS IMPAIRED DURING TUMOUR-INDUCED DYSFUNCTION
    topicImmuno-metabolism
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    Louis Picq - CIRI, Centre International de Recherche en Infectiologie, (Team Lyacts), Univ Lyon, Inserm, U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, ENS de Lyon, France
    35 | ROLE OF AMPK IN NK CELLS
    topicImmuno-metabolism
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    Ameline Hamond - Centre International de recherche en infectiologie (CIRI), France
    36 | Metformin modulates ions homeostasis to counteract tumor-induced monocyte dysfunction
    topicImmuno-metabolism
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    Mourad Aribi - Laboratory of Applied Molecular Biology and Immunology, W0414100, University of Tlemcen, Algeria
    37 | Metformin immunomodulates monocyte metabolism and respiratory burst in colorectal tumor microenvironment
    topicImmuno-metabolism
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    Mourad Aribi - Laboratory of Applied Molecular Biology and Immunology, W0414100, University of Tlemcen, Algeria
    38 | Role of polyunsaturated fatty acids in type I interpheronopathies
    topicImmuno-metabolism
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    Yasmine Messaoud-Nacer - CNRS IGMM, France
    39 | MACROPHAGES RECYCLE PHAGOCYTOSED BACTERIA TO FUEL IMMUNOMETABOLIC RESPONSES
    topicImmuno-metabolism
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    Johan Garaude - ImmunoConcEpT | CNRS | INSERM | Univ. Bordeaux, France
    40 | ROLE OF MITOCHONDRIAL TRANSLATION DURING T-CD8 RESPONSES
    topicImmuno-metabolism
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    Loane Joly - Laboratoire de Biologie et Modélisation de la Cellule - ENS DE LYON , France
    01 | NF-κB2 Transcription Factor Drives CD8⁺ T-Cell Antitumor Functions
    topicImmunotherapy
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    Khaled Bouherrou - Cancer Research Center of Lyon (CRCL) - Inserm U1052, France
    02 | NON-CANONICAL TRANSLATION OF ONCOGENES IN CANCER CELLS GENERATES SHARED AND IMMUNOGENIC NEOEPITOPES
    topicImmunotherapy
    person_pin
    Anaëlle Bolon - Centre de Recherche en Cancérologie de Lyon, UMR INSERM U1052 CNRS 5286 Université Claude Bernard Lyon 1 Centre Léon Bérard, France
    03 | ROLE OF INFLAMMATION AND TRANSCRIPTION FACTOR FOXO1 ON T-CELL EXHAUSTION IN THE COURSE OF ANTI-TUMOR IMMUNE RESPONSES
    topicImmunotherapy
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    Amélie Lombès - Institut Cochin, INSERM U1016, CNRS 8104, Université Paris Cité, France
    04 | Disruption of RINF gene (also known as CXXC5) improves persistence and antitumoral efficacy of CAR T cell therapy
     
    topicImmunotherapy
    person_pin
    Dongjie An - Université Paris Cité, Institut Cochin, INSERM, CNRS, Equipe Labélisée Ligue Nationale Contre le Cancer , France
    05 | mRNA-Based Strategies for Targeted Tumor Microenvironment Modulation to Enhance Antitumor Immunity
    topicImmunotherapy
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    Jannis Wissfeld - Division of mRNA Cancer Immunotherapies, HI-TRON Mainz, Germany
    06 | Enhancing CAR/TCR Therapy: Targeted Lipid Nanoparticles for In Vivo T Cell Engineering
    topicImmunotherapy
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    Thomas Kerzel - Helmholz Institute for Translational Oncology, mRNA Cancer Immunotherapies Division, Germany
    07 | Targeting the mono-ADP-ribosyltransferase ART1 to improve responses to radiotherapy-immunotherapy in non-small cell lung cancer
    topicImmunotherapy
    person_pin
    Erik Wennerberg - The Institute of Cancer Research, United Kingdom
    08 | AN INNOVATIVE IMMUNOTHERAPY FOR THE TREATMENT OF MELANOMA : NEOSPORA CANINUM, A MICRO-ORGANISM ENGINEERED TO SECRETE BIOMEDICINES
    topicImmunotherapy
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    laurie Lajoie - UMR 1282 - Université /INRAe-ISP-équipe BioMAP, France
    09 | TARGETING TUMOR-ANTIGEN TO FOLR2⁺ MACROPHAGES FOR T CELL ACTIVATION IN BREAST CANCER
    topicImmunotherapy
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    Judith Weber - INSERM U1016, UMR8104 and Université Paris Cité, Institut Cochin, France
    10 | Cancer immunotherapy by promoting inflammasomes in dendritic cells.
    topicImmunotherapy
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    Ikuru Kudo - Brightpath Biotherapeutics, Japan
    11 | ONTOGENY AND FUNCTIONS OF PERIPHERAL REGULATORY CD4 T CELLS AND POTENTIAL THERAPEUTIC TARGET IN CANCER 
    topicImmunotherapy
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    Sonia Carvalho - Institut Cochin, Université de Paris Cité, CNRS (UMR 8104), INSERM (U1016), France
    12 | DISSECTING THE TUMOR-REACTIVE T CELL REPERTOIRE IN MURINE PANCREATIC CANCER MODELS
    topicImmunotherapy
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    Francesca Lucato - Division of Molecular Oncology of Gastrointestinal Tumors, German Cancer Research Center, Germany
    13 | NEOSPORA CANINUM: A NOVEL APPROACH FOR CANCER IMMUNOTHERAPY
    topicImmunotherapy
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    Anne Di Tommaso - BioMAP, UMR ISP 1282 INRAe – University of Tours, France
    15 | Glatiramer Acetate Restores CD4/CD8 Balance in a Nonhuman Primate Model of SIV Infection
    topicImmunotherapy
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    Beatrice Jacquelin - Institut Pasteur, Université Paris-Cité, HIV, Inflammation and Viral Persistence Unit, France
    17 |  ROLE OF TRANSPOSABLE ELEMENTS AS NEOANTIGENS WITHIN DIFFERENT GENE ALTERATIONS IN PATIENTS WITH LUNG CANCER
    topicImmunotherapy
    person_pin
    Jeyani George Clement - Institut Curie, France
    18 | Multiomics and spatial profiling of intra tumoral immune responses from PCTS treated ex vivo with IT
    topicImmunotherapy
    person_pin
    Mathilde Persch - The Lyon Immunotherapy for Cancer Laboratory (LICL), Le Centre de Recherche en Cancérologie, UMR Inserm 1052 – CNRS 5286 – Centre Léon Bérard – UCBL, France
    20 | Antineoplastic activity of a novel tri-specific single chain antibody targeting the hERG1/b1 integrin complex and TRAIL receptors 
    topicImmunotherapy
    person_pin
    Colasurdo Rossella - University of Siena , Italy
    21 | Exploring ovarian tumors from patients with paraneoplastic neurological syndrome reveals a potential role of cytotoxic CD4 T cells in anti-tumor immunity
    topicImmunotherapy
    person_pin
    Julie Almansa - Cancer Reasearch Center of Lyon (CRCL), France
    22 | IDENTIFICATION OF KEY FACTORS INVOLVED IN ANTIGEN CROSS-PRESENTATION BY HUMAN CONVENTIONAL TYPE 1 DENDRITIC CELLS
    topicImmunotherapy
    person_pin
    Alexis Saby - CRCL, CLB, UCBL1, PLASCAN, INSERM 1052, CNRS, 5286, France
    23 | IDENTIFICATION OF A NEW TARGET ON TUMOR-ASSOCIATED REGULATORY T CELLS INVOLVED IN THE INHIBITION OF MEMORY CD8 T CELL FUNCTIONS
    topicImmunotherapy
    person_pin
    Justine Cinier - Cancer Research Center of Lyon, France
    24 | EXPLORATION OF SPATIAL IMMUNE CELL ORGANIZATION AND TRANSCRIPTOMICS SIGNATURE IN TUMOR MICROENVIRONMENT TO PREDICT ADJUVANT IMMUNOTHERAPY RESPONSE IN TRIPLE NEGATIVE BREAST CANCER PATIENTS
    topicImmunotherapy
    person_pin
    Léo Laoubi - Equipe CISTAR, labellisée 'La Ligue contre le Cancer’, Cancer Research Center of Lyon, INSERM U1052-CNRS UMR5286, Centre Léon Bérard, Université Claude Bernard Lyon1, France
    25 | NEOADJUVANT DUAL IMMUNE CHECKPOINT BLOCKADE REMODELS THE TUMOR IMMUNE LANDSCAPE AND CONDITIONS RESPONSE TO SUBSEQUENT TREATMENT IN CERVICAL CANCER PATIENTS: THE GINECO-COLIBRI STUDY
    topicImmunotherapy
    person_pin
    Bertrand Dubois - Lyon Immunotherapy for Cancer Lab, Cancer Research Center of Lyon (CRCL), INSERM U1052-CNRS UMR5286, Centre Léon Bérard, Université Claude Bernard Lyon 1, France
    26 | β-Glucan and its Structural Properties for Innate Immune-Mediated Protection Against Fungal Infections
    topicImmunotherapy
    person_pin
    Khrystyna Matvieieva - Institut Pasteur, France
    27 | DECIPHERING TREG FUNCTIONS AND MECHANISMS AT EARLY STAGES IN A SPONTANEOUS SPORADIC BASAL-LIKE MURINE TUMOR MODEL
    topicImmunotherapy
    person_pin
    Thibaut Barbe - “Cancer Immune Surveillance & Therapeutic Targeting” Team, Cancer Research Center of Lyon, INSERM 1052 - CNRS 5286, Centre Léon Bérard, Université de Lyon, Université Claude Bernard Lyon 1, 69008 Lyon, France, France
    28 | CHRONIC HAND ECZEMA IS A TYPE 2 DISEASE: EVIDENCES FROM INTEGRATED CLINICAL TRIAL AND MOLECULAR PROFILING
    topicImmunotherapy
    person_pin
    Perrine Gery - Centre International de Recherche en Infectiologie, University of Lyon 1 and École Normale Supérieure de Lyon; Inserm U1111, France
    29 | Metformin modulates lipid immunometabolism and reduces inflammasome activation in tumor-exposed monocytes
    topicImmunotherapy
    person_pin
    Mourad Aribi - Laboratory of Applied Molecular Biology and Immunology, W0414100, University of Tlemcen, Algeria
    30 | ROLE OF CDKN2A IN REGULATING THE IMMUNE TUMOR MICROENVIRONMENT IN MOUSE MODELS OF PANCREATIC DUCTAL ADENOCARCINOMA (PDAC)
    topicImmunotherapy
    person_pin
    Jeanne Magnan - INSERM, IMRB U955, Université Paris-Est Créteil Val de Marne, France
    31 | FUNCTIONAL CONSEQUENCES OF THE GENOMIC DELETION OF PD-1 AND TIGIT ON MELANOMA-SPECIFIC T LYMPHOCYTES
    topicImmunotherapy
    person_pin
    James Goward - Immunology and New Concepts in ImmunoTherapy, INCIT, Nantes Université, Université d'Angers, Inserm, Nantes, France, France
    32 | ROLE OF THE FOXO1 TRANSCRIPTION FACTOR IN THE HOMEOSTASIS OF REGULATORY T CELL SUBPOPULATIONS AND POTENTIAL THERAPEUTIC TARGET IN CANCER
     
    topicImmunotherapy
    person_pin
    Léa Giraud - Institut Cochin, CNRS (UMR 8104), INSERM (U1016), Université de Paris Cité, France
    33 | SPATIAL ECOSYSTEMS OF TUMOR CELL STATES AND IMMUNE CELLS SHAPE THE EFFICACY OF ANTI-PD1 IMMUNOTHERAPY IN CUTANEOUS MELANOMA
    topicImmunotherapy
    person_pin
    Félix Pham - Department of Dermatology, Centre Hospitalier Lyon Sud, Hospices Civils de Lyon, Lyon 1 University, France
    34 | TCR AFFINITY-DEPENDENT REGULATION OF T CELL ACTIVATION BY THE IMMUNOSUPPRESSIVE ENZYME IL4I1
    topicImmunotherapy
    person_pin
    Charlotte Nidercorne - INSERM, IMRB U955, Université Paris-Est Créteil, Créteil, France , France
    35 | GOVERNING IMMUNOGENIC CELL DEATH THROUGH TRANSCRIPTIONAL AND TRANSLATIONAL CONTROL
    topicImmunotherapy
    person_pin
    Taja ŽEleznik Ramuta - National Institute of Chemistry, Slovenia
    36 | Evaluation of CCR8 as an anchor for the development of therapies specific to T regulatory lymphocytes infiltrating the tumor microenvironment in solid cancers 
    topicImmunotherapy
    person_pin
    Julia Eterradossi - Cancer Research Center of Lyon, France
    37 | IFN-γ INDUCES CASPASE-3- AND IRF1-INDEPENDANT CELL DEATH WITH CHEMOTERAPY IN A LEUKEMIA CELL LINE MODEL.
    topicImmunotherapy
    person_pin
    Brice Lagrange - UCLy (Lyon Catholic University), ESTBB, France
    39 | The role of myeloid cells in skull-to-brain axis & neuroinflammation
    topicNeuro-immunology
    person_pin
    Elisa Eme-Scolan - Centre d'Immunologie de Marseille Luminy, France
    40 | Modeling COVID-19 Pathogenesis and Brainstem-Driven Respiratory Dysfunction in hACE2 Knock-In Mice
    topicNeuro-immunology
    person_pin
    Ana Zarubica - CIPHE-INSERM-CNRS-AMU-Celphedia, France
    01 | Effect of fever-range hyperthermia on the humoral immune response
    topicVaccination against pathogens and cancers
    person_pin
    Marie Le Borgne - INSERM U1148 “Laboratory for Vascular Translational Science”, France
    02 | DEVELOPMENT OF A NEW THERAPEUTIC VACCINATION STRATEGY BASED ON LONG ARTIFICIAL SYNTHETIC PEPTIDES IN MELANOMA.
    topicVaccination against pathogens and cancers
    person_pin
    Amélie Guiho - Immunology and New Concepts in ImmunoTherapy, INCIT, Nantes Université, Université d'Angers, Inserm, France
    03 | A Tumor-Derived Soluble DAMP Ligand Activates TREM1 to Enhance Anti-Tumor Immunity
    topicVaccination against pathogens and cancers
    person_pin
    Chien-Jung Li - Institute of Microbiology and Immunology, National Yang Ming Chiao Tung University, Taiwan
    04 | Targeting the splicing machinery to modulate exonisation of transposable elements and tumour immunogenicity
     
    topicVaccination against pathogens and cancers
    person_pin
    Laura Charnay - U932, Institut Curie, France
    05 | IMMUNE STIMULATING PROPERTIES OF LNP FORMULATIONS CONTAINING A PEG ALTERNATIVE
     
    topicVaccination against pathogens and cancers
    person_pin
    Christine Rueckert - CureVac SE, Germany
    06 | Critical COVID-19 unveils the link between viral particle blood dissemination and prolonged Type I Interferon
    topicInfections and immune responses
    person_pin
    William Mouton - Hospices Civils de Lyon, France
    07 | HLA-E-dependent adaptations of NKG2A+ and NKG2C+ NK cells in people living with HIV
    topicInfections and immune responses
    person_pin
    Emma Beaumont - Institut Pasteur, Université Paris-Cité, HIV Inflammation & Viral Persistences Unit, France
    08 | Role of the inflammasome pathway in the expansion and functions of regulatory plasma cells during sepsis
    topicInfections and immune responses
    person_pin
    Clara Vigneron - Equipe Inflammasome NLRP3 et réponse immunitaire au sepsis - Centre International de Recherche en Infectiologie, France
    09 | CYLD PROTEOLYSIS BY CASPASE-3, A CHECKPOINT TO BALANCE INFLAMMATION DURING MITOCHONDRIAL APOPTOSIS?
    topicInfections and immune responses
    person_pin
    Yanis Macé - SOAP Team, CRCI2NA, INSERM U1307, CNRS U6075, Nantes Université, Université d’Angers, France
    10 | Vaccination prevents immune suppression and tissue disruption in LCMV-induced Post-Acute Syndromes
    topicInfections and immune responses
    person_pin
    Paula Cebollada Rica - Universitat Pompeu Fabra, Spain
    11 | Oral tongue cancer infectome in patients with no identified risk factors
    topicInfections and immune responses
    person_pin
    Julia S. Bruno - International Agency for Research Cancer (IARC) – World Health Organization, France
    12 | HTLV-1-INFECTED T CELLS AND DENDRITIC CELLS: A RECIPROCAL MANIPULATION?
    topicInfections and immune responses
    person_pin
    Maroua Haouam - Centre International de Recherche en Infectiologie, Retroviral Oncogenesis, Inserm U1111—Université Claude Bernard Lyon 1, CNRS, UMR5308, Ecole Normale Supérieure de Lyon , France
    13 | Altered NK Cell Phenotype in Antiviral-Treated Chronic Hepatitis B Patients
    topicInfections and immune responses
    person_pin
    Emily Sible - CIRI, Centre International de Recherche en Infectiologie, Univ. Lyon, Inserm, U1111, Université Claude Bernard Lyon 1, CNRS, UMR5308, ENS de Lyon, France
    14 | SIRPα is an inhibitory receptor that regulates NK cell activation and function
    topicInfections and immune responses
    person_pin
    Lamin B Cham - Arabian Gulf University, Bahrain
    15 | Bovine Meat and Milk Factors (BMMF) – Putative Biomarkers for Cancer in the Context of Dietary Exposure and Inflammation
    topicInfections and immune responses
    person_pin
    Oladimeji Paul Duduyemi - German Cancer Research Center (DKFZ), Germany
    16 | Bovine Meat and Milk Factors (BMMF) - Putative Biomarkers for Cancer in the Context of Dietary Exposure and Inflammation
    topicInfections and immune responses
    person_pin
    Timo Bund - German Cancer Research Center (DKFZ), Germany
    17 | Functional alteration of MAIT cells in Hidradenitis Suppurativa patients
    topicInfections and immune responses
    person_pin
    Alexis Dumas - INSERM U1111 - CIRI-Centre International de Recherche en Infectiologie, France
    18 | Link between bovine meat and milk factor protein expression and inflammation as possible driver of colorectal cancer – new options for prevention and therapy?
    topicInfections and immune responses
    person_pin
    Gunjan Shukla - DKFZ, University of Heidelberg, Germany
    19 | Inefficient CTL Surveillance of Human Oncoretrovirus During Cancer Development 
    topicInfections and immune responses
    person_pin
    Devon Weterings - Department of Infectious Disease, Imperial College London, United Kingdom
    21 | DECIPHERING THE ROLE OF THE INTRATUMORAL MICROBIOME IN EPITHELIAL OVARIAN CANCER: APPLICATION OF A BIOINFORMATIC PIPELINE TO ANALYSE MICROBIOME DIVERSITY USING BULK RNAseq DATA
    topicInfections and immune responses
    person_pin
    Léa Ikhlef - Centre de Recherche en Cancérologie de Lyon (CRCL), UMR INSERM U1052 CNRS 5286, Centre Léon Bérard, France
    22 | Characterization of IFN-I response impairments through immune functional assays in person who experienced mild or severe form of COVID-19
    topicInfections and immune responses
    person_pin
    Marion Debombourg - Laboratoire Commun de Recherche HCL-bioMérieux, France
    23 | COCHLIN SOLUBLE FRACTION LCCL BINDS TO APOPTOTIC CELLS AND ENHANCES EFFEROCYTOSIS
    topicInfections and immune responses
    person_pin
    Louise Courcol - CIRI, Centre International de Recherche en Infectiologie, Inserm U1111, Université Claude Bernard Lyon 1, CNRS UMR5308, ENS de Lyon, France
    24 | A MULTI-OMICS APPROACH TO ASSESS THE ONCOGENIC AND INFLAMMATORY POTENTIAL OF VIRAL ONCOPROTEINS TAX FROM NEGLECTED HTLV-1 GENOTYPES
    topicInfections and immune responses
    person_pin
    Thomas Duchateau - Centre International de Recherche en Infectiologie (CIRI), France
    25 | THE HIV-1 SILENCER BCL11B/CTIP2 REGULATES THE TLR3-MEDIATED CELLULAR RESPONSE TO VIRAL INFECTIONS IN MICROGLIAL CELLS.
    topicInfections and immune responses
    person_pin
    Muhammad Kashif - Molecular Virology, IUT LOUIS PASTEUR, University of Strasbourg, France
    26 | CYTOTOXIC CD8+ T CELLS ARE ASSOCIATED WITH PROTECTION OF PIGS AGAINST AFRICAN SWINE FEVER VIRUS
    topicInfections and immune responses
    person_pin
    Jordi Argilaguet - IRTA, Animal Health, Centre de Recerca en Sanitat Animal (CReSA), Spain
    27 | DISTINCT TISSUE-RESIDENT MEMORY T CELLS PERSIST IN THE EPIDERMIS OF ALLERGIC CONTACT DERMATITIS
    topicInfections and immune responses
    person_pin
    Roxane Cuzin - Centre International de Recherche en Infectiologie - INSERM U1111, France
    28 | Marine sulphated polysaccharides stimulate innate immunity to fight infection in a model of post-traumatic immunosuppression
    topicInfections and immune responses
    person_pin
    Maëva Guillonneau - Olgram SAS, France
    29 | POST-TRANSCRIPTIONAL REGULATION OF T CELL ACTIVATION IN CANCER
    topicInfections and immune responses
    person_pin
    Trang-My Nguyen - Toulouse Institute for Infectious and Inflammatory Diseases - Inserm, France
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